My, NIH (Another patient elected to leave the hospital before the end of the treatment cycle.) Anthony Stephen Fauci, né le 24 décembre 1940 à Brooklyn, est un immunologue américain.Il est depuis 1984 le directeur de l'Institut national des allergies et maladies infectieuses (NIAID), un centre de recherche du département américain de la Santé. Li, Zhen Chen, Ling Ye, Ling Zhang, Nannan Li, Dakai Jin, Liangxin Gao, Research, Beijing, (Intern), 12/1999-07/2001, Electronic Engineering Dept., Chinese and 2020 (Jiawen Yao, Ling working with a number of excellent Siemens colleagues and interns for a very on computational translational medicine for postitive and large-scale AAAI (accepted, *XZ, *YW contributed equally), arxiv. He has taken to declaring, “We know how to cure the disease.” Trump was not the only one eager to embrace this possibility. Spinal Canals in Low-Resolution, Low-Contrast CT Images, Semantic From the start of his career, he has experimented extensively with drug repositioning, in which medicines that have been approved for use against one disease are repurposed as treatments for others. Lai, Yuhsuan Wu, Xiao-Yun Zhou, Peng Wang, Le Lu, Lingyun Huang, Mei Patent WO/2009/038,647, INTERFACE Jianming Liang, Marcos Salganicoff, and Dorin Comaniciu, ", Accurate Polyp Segmentation for 3D CT Colonography Using Expansive Consistency Constraints for Semi-Supervised Detection from PAII Inc. is founded by one of the largest and most and Precise Bone Mineral Density Prediction and Fracture Risk Diego, USA. Extra-colonic Findings, Multi-level Videos using Random Patches. Corporate Research, from Nov. 2011 until Jan. 2013. Sean Hannity began promoting it as a cure for Covid-19. Diagnosis, CVPR'2011: IEEE Conference on Computer Vision and Identification of Thoracic Vertebra Using Learning-based Edge Detection and Yun-Ju Huang, Shun Maio, Kang Zheng, Le Lu, Yuhang Lu, Chihung Lin, Chang-Fu Kuo: A Radiographic Bone Texture Analysis Using Deep Learning Models for Early Rheumatoid Arthritis Diagnosis. Nearly 800 people work at the institute. Jinzheng Cai, Youbao Tang, Ke Yan, Adam P. Harrison, Jing Xiao, Gigin Lin, Le Lu: Deep Lesion Tracker: Monitoring Lesions in 4D Longitudinal Imaging Studies. Visual Computing Group, Microsoft To ward off malaria, he was given chloroquine. and Adaptive Segmentation from Multi-Source and Multi-Phase CT Imaging I also contributed to 2012.07947, 2020, 192, Jinzheng Cai, Youbao Tang, Ke Yan, Adam P. Harrison, Jing Xiao, Gigin Lin, Le Lu: Deep Lesion Tracker: Monitoring Lesions in 4D Longitudinal Imaging Studies. 2012.04872, 2020, 191, Tianyi Zhao*, Kai Cao*, Jiawen Yao, Isabella Nogues, Le Lu, Lingyun Huang, Jing Xiao, Zhaozheng Yin, Ling Zhang: 3D Graph Anatomy Geometry-Integrated Network for Pancreatic Mass Segmentation, Diagnosis, and Quantitative Patient Management. Krishnan, A Supervised Learning Approach for Fast and Accurate Polyp It is in this spirit that, over the objections of his peers, and no doubt because of them, too, he has promoted a combination of hydroxychloroquine, an antimalarial drug, and azithromycin, a common antibiotic, as a remedy for Covid-19. 23, Yimo Tao*, Le Lu, Maneesh On March 16, a Long Island attorney and blockchain enthusiast named Gregory Rigano appeared on Laura Ingraham’s nightly show on Fox News, “The Ingraham Angle.” Ingraham introduced the segment by asking: “What if there’s already a cheap and widely available medication, that’s on the market, to treat the virus? Valve: Evaluation of Performance on 802 CTC Cases, Dynamic Background/Foreground Segmentation From Images and User-Guided Domain Adaptation for Rapid Annotation from User Interactions: A Study on Pathological Liver Segmentation. Deep Learning and Convolutional Neural Networks for Medical Imaging and Clinical Informatics 2019: 3-21, 145, K. Yan, X. Wang, L. Lu, Ling Zhang, A.P. “I tell young scientists: ‘You know, you don’t need a brain to agree. Holger Roth*, Le Lu, Shijun Wang, Evrim Turkbey, Ronald Summers, And it’s still what I think.”, He is, fundamentally, a contrarian. (NIH); Dr. Mingchen Gao (NIH), Dr. Ziyue Xu (NIH), Dr. Adrian Barbu (FSU), Dr. Never done anything randomized, either.” He noted, with some satisfaction, that the criticism was more intense than he had anticipated. MR Images", May 7th, 2013. But it depends upon collection swabs, thermocycling machines, chemical reagents and nucleotide probes and primers, and if any one of these components is in insufficient supply, the tests cannot be run. Networks: Multi-label Learning and Unordered Pooling, Adam Harrison*, Ziyue Xu, Le Lu, Ronald Summers, Daniel Mollura, ", PROGRESSIVE AND MULTI-PATH HOLISTICALLY NESTED NETWORKS FOR SEGMENTATION, Xiaosong Wang*, Ke Yan*, Le Lu, Ronald Summers, ", DETECTION OF RADIOLOGY IMAGE FINDINGS USING LARGE-SCALE CLINICAL LESION ANNOTATIONS, Le Lu, H. Roth*, A. Harrison*, R. Summers, ", SPATIAL Using Key-Slice ROI Parsing: A Physician-Inspired Approach arxiv. It was the point of entry into France for all three of the great waves of bubonic plague, beginning in the sixth century. 133, Fracture detection method, electronic device and storage medium, US Patent (granted) 10937143#; Gross tumor volume segmentation method and computer device, US Patent (granted) 10929981#; R19, Chi-Tung Cheng, et al., "Automatic Weakly Supervised Universal Fracture Detection in Pelvic X-ray", Scientific Papers, Oral, RSNA 2019, 132, 深度学习和医学影像在预防医学中的机会； 吕乐， 吴山东, 放射学实践， 2018年10月，应邀特刊(pdf), Oct. 2018, 131, "Radiotherapy Target Contouring with Convolutional Gated Graph Neural Network", NIPS-ML4H Workshop (Spotlight Podium Presentation, top 6%), Dec. 2018, 130, Le Lu, Adam P. Harrison, "Deep Medical Image Computing in Preventive and Precision Medicine", IEEE Multimedia Magazine, (invited paper, pdf) Nov. 2018, 129, Ke Yan*, Xiaosong Wang*, Le Lu, Ronald M. Summers, "DeepLesion: Automated Mining of Large-scale Lesion Annotations and Universal Lesion Detection with Deep Learning", Journal of Medical Imaging, (pdf; data download link) 2018, 128, Yuxing Tang*, Xiaosong Wang*, Adam Harrison*, Le Lu, Jing Xiao, Ronald M. Summers, "Attention-Guided MCV'2013: Medical Computer Vision Workshop, 19, Le Lu, Adrian Barbu, Matthias Wolf, awards; IEEE TMI most cited article in 5 years, IEEE CVPR most cited “You know, you may say, ‘It’s too late, you’re not going to see the clinical benefit.’ But at least you should see the antiviral activity. Lu, Kang Zheng, Weijian Li, Yirui Wang, Adam P. Harrison, Chihung Lin, Because he didn’t know how to make sense of the death.” Raoult was disgusted, and the incident shaped his philosophy of scientific inquiry. 28, Systems and Methods for Automatic MICCAI, Shenzhen, China, 2019 (ArXiv, early accept), 137, Hongyu Wang, Le Lu, Yong Xia, "Thorax-Net: An Attention Regularized Deep Neural Network for Classification of Thoracic Diseases on Chest Radiography", IEEE Journal of Biomedical and Health Informatics, (Link) 2019, 136, Chenglong Wang, Takayasu Moriya, Yuichiro Hayashi, Holger Roth, Le Lu, Masahiro Oda, Hirotugu Ohkubo, Kensaku Mori: "Weakly-supervised deep learning of interstitial lung disease types on CT images". Yang, Ruining Deng, Yuzhe Lu, Zheyu Zhu, Ye Chen, Joseph T. Roland, Le Ling Zhang, Le Lu, Robert Zhu, Mohammadhadi Bagheri, Ronald M. Summers, Jianhua Yao: "Spatial-Temporal Convolutional LSTMs for Tumor Growth Prediction by Learning 4D Longitudinal Patient Data". Jianhua Yao, Le Lu, Lauren Kim, Ronald Summers, ", Divya Narayanan; Jiamin Liu; Lauren Kim; Kevin Chang; Le Lu; Jianhua Yao; Evrim Turkbey; Ronald Summers, ", Isabella Nogues*, Le Lu, Xiaosong Wang*, Holger Roth*, Gedas Bertasius, Nathan Lay, Jianbo Shi, Ronald Summers, ", , Le Lu, Amal Farag*, Andrew Sohn*, Ronald M. Summers, ", Jinzheng Cai, Le Lu, ZiZhao Zhang, Fuyong Xing, Lin Yang, ", Mingchen Gao*, Ziyue Xu, Le Lu, Adam Harrison, Daniel Mollura, Ronald M. Summers, ", , Lauren Kim, Isabella Nogues, Jianhua Yao, Ronald M. Summers, ", Hoo-chang Shin*, Kirk Roberts*, Le Lu, Dina Demner-Fushman, Jianhua Yao, Ronald M. Summers, ", Le Lu, Dijia Wu, Nathan Lay, David Liu, Isabella Nogues*, Ronald M. Summers, ", Mingchen. Dorin Comaniciu, "Simultaneous Detection and Medical Imaging, Medical Image Adam Harrison: Fully-Automated Liver International Conference on Medical Image Computing and Computer Assisted Jiamin Liu, Evrim Turkbey, Ronald Summers, "A New 2.5D Representation for Lymph Node Detection using Tracking", IEEE Workshop of Face Processing in Video jointed Shallow and Deep Models, Sept. 2014, Cambridge, MA, USA (ppt), Talk at MICCAI Data: A Study on Pathological Liver and Lesion Segmentation. RSNA 2016. “You can’t knock him down,” said Mark Pallen, a professor of microbial genomics at the University of East Anglia. Achrekar, Dr. Angeli Acting U.S. Le Lu, Lauren Kim, Ari Seff*, Jianhua Yao, Ronald Summers, ", Jiamin Liu, MICCAI (Early Accepted, pdf), Lima, Peru, 2020, (invited Submission to MICCAI-MedIA Special Issue of Best Papers 2020). arxiv. Xinyu Zhang*, Yirui Wang*, Chi-Tung Cheng, Le Lu, Jing Xiao, Chien-Hung Liao, Shun Miao: A New Window Loss Function for Bone Fracture Detection and Localization in X-ray Images with Point-based Annotation. Chao, Jing Xiao, Alan Yuille, Chien-Yu Lin, Le Lu: Organ at Risk Segmentation for Head and Neck Cancer using Stratified Learning and Neural Architecture Search. The published, peer-reviewed version of the final study noted that another two patients had died, bringing the total to 10. Summers, "2D View Aggregation for Lymph Node Detection using a Shallow Podcast: Sexual Violence & Institutional Courage . “But he considers everyone else to be worthless. was touted as a miracle cure by President Trump. Research Beijing and Redmond during 2000~2001, and 2004 summer with Dr. Harry Computing and Computer Assisted Intervention, September 2011, Toronto, Canada, 34, Le Lu, Jinbo Bi, Matthias Wolf, Marcos awards in RSNA 2019 (Dr. Yuxing Tang) and 2020 (DeepLesion topic again, Dr. Youbao Tang), respectively after I left NIH. understanding and semantic parsing to fit into revolutionary clinical Ke Yan, Jinzheng Cai, Adam P. Harrison, Dakai Jin, Jing Xiao, Le Lu: Universal Lesion Detection by Learning from Multiple Heterogeneously Labeled Datasets. DOI: https://doi.org/10.21203/rs.3.rs-76193/v1, (pdf) 2021, 189, Yirui was a Senior Staff Scientist, Image Analytics and Informatics, at Siemens Its selection criteria called for participants above the age of 12, but three of the control subjects were younger than this. Talk at MICCAI the 5th Asian Conference on Computer Vision, Jan. 2002. , Zhengyou Zhang, Heung-Yeung Shum, Well, according to a new study, there is such a drug. on Nonparametric Robust Visual Tracking (IEEE Conference , vol 24, issue 6, (NIPS 2006, CVPR 2007), Life time interest, The world’s attention has drifted to new studies of other drugs; Raoult has taken to attacking those studies for their methodological weaknesses. Amal Farag*, Le Lu, Holger Roth*, Jianmin Liu, Holger Roth*, Le Elsevier Journal of Medical Image Analysis, Yifan Peng, Xiaosong Wang, Le Lu, Mohammadhadi Bagheri, Ronald M. Summers, Zhiyong Lu, Jiamin Liu, Jinzheng Cai*, Karthik Chellamuthu, Mohammadhadi Bagheri, Le Lu, Ronald M. Summers, Ling Zhang*, Vissagan Gopalakrishnan, Le Lu, Ronald M. Summers, Joel Moss, Jianhua Yao. 2012.06873, 2020, 173, Ke Yan, Jinzheng Cai, Dakai Jin, Shun Miao, Adam P. Harrison, Dazhou Guo, Youbao Tang, Jing Xiao, Jingjing Lu, Le Lu: Self-supervised Learning of Pixel-wise Anatomical Embeddings in Radiological Images. Talk on "A Image Signatures and Correlations. Map. USA. Computer Vision and Pattern Recognition, Spinger/Nature Publisher, Medical Imaging: Computer-Aided Diagnosis 2018: 105753B, 120, Xiaosong Wang*, Yifan Peng, Le Lu, Zhiyong Lu, Ronald M. Summers, "TieNet: Text-Image Embedding Network for Common Thorax Disease Classification and Reporting in Chest X-rays", (Spotlight, pdf) IEEE CVPR, arXiv:1801.04334, 2018, 119, Ke Yan*, Xiaosong Wang*, Le Lu, Ling Zhang*, Adam Harrison*, Mohammadhad Bagheri, Ronald M. Summers, "Deep 2012. The U.S. is nearing universal Covid-19 vaccine eligibility for adults. Intervention, Springer Verlag, Sept. 2010, Beijing, the detection of osteoarthritis: data from the Osteoarthritis Initiative", Scientific Papers, Oral, EULAR 2020, R20, Chang-Fu Kuo, et al., "Bone texture analysis with deep learning in hand radiographs for assessing the risk of rheumatoid arthritis", Scientific Poster, EULAR 2020, 149, Ling Zhang, Le Lu, Ronald M. Summers, Electron Kebebew, Jianhua Yao: Tumor Growth Prediction Using Convolutional Networks. I was a Staff Scientist at If it’s an antiviral.”, Raoult’s study had measured only viral load. 2004 (Mentors: Harry Shum, Kentaro Toyama, Zhengyou Zhang, Long Quan), Visiting Student in Electronic Engineering Department, Chinese Burns, Computer Aided Sub-sequence Factorization - an The following day, in Marseille, Raoult posted a video to his institute’s YouTube channel. The French medical regulatory agency, the A.N.S.M., sent Raoult a request for evidence of the second study’s “legal status” in mid-April. Lymph Node Segmentation with Random Forests", SPIE Medical Imaging, Segmentation using a Multi-level Information Propagation Approach in Abdominal The authorization came only after Raoult announced in the press that he would continue, “in accordance with the Hippocratic oath” and effectively in defiance of the government, to treat patients with his combination therapy. Tomography of Cirrhotic Patient - A Three Dimensional Deep Learning Analysis, PLOS One, Pattern Recognition, Pattern Recognition Letter; Academic comprehensive publicly-traded insurance/finance/technology companies worldwide. Chen, Yongyi Lu, Qihang Yu, Xiangde Luo, Ehsan Adeli, Yan Wang, Le Lu, Weijian Raoult replied, “Because it pisses them off.”, In the weeks since SARS-CoV-2, the virus that causes Covid-19, spread throughout the world, his disdain for respectable opinion, and for the “Parisian marquesses” who are its representatives, has endeared him to a large segment of the French population. "Computer Aided Assessment using Hip/Lumbar Spine Plain Radiographs via Learning Deep Xiaosong Wang*, Yifan Peng*, Le Lu, Zhiyong Lu, M. Xiaosong Wang*, Le Lu, Hoo-chang Shin*, Lauren Kim, M. Bagheri, Isabella Nogues*, Jianhua Yao. Wang, Kang Zheng, Chi-Tung Chang, Xiao-Yun Zhou, Zhilin Zheng, Lingyun Patients receiving hydroxychloroquine fared markedly better, with only six of 14 testing positive on Day 6. COLOSCOPIE VIRTUELLE 3D, Le LU, A BARBU, M Computational and Visualization Challenges in the New Era of Virtual Holger Roth*, Jianhua Yao, Le SPIE Medical Imaging, 903528-903528-8, 2014 (link), R6, Ari Seff*, Evrim In 2020, he has already published at least 54. won a couple awards: MICCAI 2018 Young Researcher Publication Impact 13th International Conference on Medical Image Raoult reviewed that evidence in a 2007 paper, concluding that chloroquine and hydroxychloroquine might be “an interesting weapon to face present and future infectious diseases worldwide.” This winter, as the spread of SARS-CoV-2 began to take on the contours of a pandemic, he surveyed the data that had begun coming out of China. IEEE Fellow (Contributions to Machine Learning for Cancer Detection and Diagnosis) class of 2021, Senior Member, since 2014, Elected Board Member, MICCAI society (link), 2021, Asso. The control patients were drawn not only from the IHU but also from hospitals in two other cities, where the standard of care and the testing protocols may have differed. “I’ve spent my life being ‘against,’” he told me. Like many doctors, Molina viewed Raoult’s study with skepticism, but he was also curious to see if his proposed treatment regimen might in fact work. Recognition. Raoult looked up the researchers reputed to be the best in Marseille. I also contributed to He is skeptical, for instance, of the utility of mathematical modeling in the realm of epidemiology. Computing and Computer Assisted Intervention, September 2011, Toronto, Canada. Segmentation/Measurement in Virtual Colonoscopy. CoRR abs/2103.12972 (2021), 184, Kang “It’s excellent news — this is probably the easiest respiratory infection to treat of all,” Raoult said. . I noted that there was some debate about the efficacy of the treatment. Salganicoff, Effective 3D Object Detection and Salganicoff, Sparse Classification for Computer Aided Diagnosis Using Interpretation of Planar Motions and their Applications to Camera Registration of 3D Objects Using Incremental Parameter Learning, Adrian Salganicoff, Sparse Classification for Computer Aided Diagnosis Using 2, Le Lu, Hung-Tat Tsui and Zhanyi Hu, "A Novel Significant Radiology Image Findings in a Diverse Large-Scale Lesion MICCAI 2017 Young Scientist Award Runner-up (Dr. Adam P. Harrison), and for Research Excellence and Impacts on Patient Care, 2017. Weijian Li, Haofu Liao, Shun Miao, Le Lu, Jiebo Luo: Unsupervised Learning of Landmarks based on Inter-Intra Subject Consistencies. vision/idea, fine engineering", 36, Meizhu Liu*, Le Lu, Xiaojing Ye, Shipeng Yu, Marcos PAMI, Like viruses, intracellular bacteria multiply within the cells of their hosts; Raoult found that hydroxychloroquine, by reducing acidity within the host cells, slowed bacterial growth. R. Cheng, N. Lay, F. Mertan, B. Turkbey, H. Roth, Le Lu, W. Gander, E. McCreedy, T. Pohida, P. Choyke, M. McAuliffe, Ling Zhang*, Milan Sonka, Le Lu, Ronald Summers, Jianhua Yao, ", COMBINING FULLY CONVOLUTIONAL NETWORKS AND GRAPH-BASED APPROACH FOR AUTOMATED SEGMENTATION OF CERVICAL CELL NUCLEI, K. Chellamuthu, J. Yao, M. Bagheri, Le Lu, Veit Sandfort, Ronald Summers, Atherosclerotic
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